Prevalence of Csh-like fibrillar surface proteins among mitis group oral streptococci

The prevalence of Csh-like fibrillar surface proteins among oral streptococci was investigated by ELISA and by immunoelectron microscopy using antiserum raised to recombinant fragments of CshA of Streptococcus gordonii DL1. The majority of S. gordonii, Streptococcus sanguis and Streptococcus oralis strains tested elaborated short (ca. 50-80 nm long) surface fibrils …

Distribution of CshA Fibrils amongst Mitis Group Oral Streptococci

Many oral streptococci express large surface structures (fibrils and fimbriae) that have been implicated in adhesion of bacteria to oral surfaces. Streptococcus gordonii DL1 short peritrichous fibrils (61 nm long) are composed of cell-wall-anchored CshA adhesin (259 kDa). ELISA studies have previously shown that proteins immunologically related to CshA are …

BSc (hons) Microbiology (sandwich)

Degree classification: First class Faculty of Science and Engineering, The University of Manchester. Industrial experience (sandwich placement) Quorn Plant Quality Laboratory, Billingham. Project Detection of CshA Polypeptide on the Cell Surface of Oral Streptococci (supervised by Dr Pauline Handley)